![]() ![]() My son’s former boyfriend has stayed in touch with my ex-wife and me and we care for him a great deal. He wrote me a letter of apology, but I ripped it into pieces and threw it in the garbage after barely scanning it.ġ4. For his crime, he was incarcerated 18 months, then released. But Sugar, for this and other things, I am tormented anyway.ġ3. I believe he knew I wanted him to be happy, no matter what path his happiness might take. I didn’t quite believe him or understand, so I inquired in a negative tone: but how can you not like girls? I quickly came to embrace him for who he was, but I regret my initial reaction to his homosexuality and I never apologized to him for it. ![]() One thing I would change is when, at 17, my son informed me he was gay. About the things he would be doing now if he were alive and also the things I did with him when he was young, my good memories of him, my wish to go back in time and either relive happy memories or alter those that are less happy.ġ2. Sometimes the pain is so great I simply lie in my bed and wail.ġ1. In short, I’m going on with things in a way that makes it appear like I’m adjusting to life without my son, but the fact is I’m living a private hell. In addition, I have a rewarding job, good health, and a girlfriend whom I love and respect.ġ0. I have good friends who are supportive of me, my brother and sister-in-law and two nieces are a loving and attentive family to me, and even my ex-wife and I have become close friends again since our son’s death-we’d been cold to one another since our divorce when our son was 15.ĩ. Given the circumstance, ending my life is a reasonable thought, but I can’t do it because it would be a betrayal of my values and also of the values I instilled in my son.Ĩ. Suicide has occurred to me (this is what initially prompted me to make an appointment with my psychologist). I see a psychologist regularly and I’m not clinically depressed or on medication.ħ. I’ve never told you this because I’m not the type to write comments on web sites or send fan notes, but I’d like to say it now, in hopes that even if you opt not to publish this, you’ll read it and receive my gratitude for the comfort you’ve given me.Ħ. I have faith in my version of God and I pray every day and the way I feel when I’m in my deepest prayer is the way I feel when I read your words. No matter what you’re writing about, even if the particular situation has nothing to do with my life, your words feel sacred to me. My life has been a lot different from yours, but your big heart moves me. I can’t explain it, Sugar, but it’s true. Most days it feels like my grief is going to kill me, or maybe it already has. The dear boy I loved more than life itself was dead before the paramedics even got to him. DEAR SUGAR RUMPUS FULLThe man was so inebriated he drove through a red light and hit my son at full speed. DEAR SUGAR RUMPUS DRIVERNearly four years ago, a drunk driver killed my son. ![]() That’s all I ask for and it’s not a question.ģ. I don’t have a definite question for you. You may change it to a regular letter if you wish to should you choose to publish it.Ģ. This is a hard subject and a list helps me contain it. The only way I can get it out is to make a list instead of write a letter. It’s taken me many weeks to compose this letter and even still, I can’t do it right. Even in the flaws, there is a buried truth - it's that second beating heart that you needed to see for yourself.1. From Sugar, I learned that our most vital development happens through commitment to the work, even if that work comes out misshapen or in terrible need of a copy edit. Not because I think I'm Tolstoy now, or because I have a six-figure deal (ha!) but because in that agonizing process I discovered things about myself and my characters that I would never have learned if I had not gone the distance - the kinds of things that shift your perspective on the world just a little bit, as much as a trip to France or an Ivy League MFA or whatever else it is that artists are supposed to do to cultivate themselves. Whether the novel ever finds readers is a question that remains to be decided, but the work of birthing that book was essential, an end in itself. Every day I stared at the page feeling a bit sick, but knew it was more important to plunge ahead than to founder on the shoals of my own ego, my desire to produce sentence upon sentence of pure genius. Haunted by the prospect of endless packing, landlord logistics, and ever so much more, I grabbed onto that second beating heart and pulled. ![]()
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![]() ![]() tahitensis, grown in the South Pacific and V. fragrans), grown on Madagascar, Réunion, and other tropical areas along the Indian Ocean V. Three major species of vanilla currently are grown globally, all of which derive from a species originally found in Mesoamerica, including parts of modern-day Mexico. By the end of the 20th century, Albius was considered the true discoverer. Noted French botanist and plant collector Jean Michel Claude Richard falsely claimed to have discovered the technique three or four years earlier. Hand-pollination allowed global cultivation of the plant. In 1841, Edmond Albius, a 12-year-old slave child who lived on the French island of Réunion in the Indian Ocean, discovered that the plant could be hand-pollinated. The method proved financially unworkable and was not deployed commercially. In 1837, Belgian botanist Charles François Antoine Morren discovered this fact and pioneered a method of artificially pollinating the plant. Pollination is required to make the plants produce the fruit from which the vanilla spice is obtained. #WHERE DOES VANILLA COME FROM FULL#And don’t waste the empty vanilla pod, which is full of flavor! Add it to a jar of sugar or to milk/cream for a delicate vanilla flavor.Vanilla is a spice derived from orchids of the genus Vanilla, primarily obtained from pods of the Mexican species, flat-leaved vanilla ( V. planifolia). Repeat with the other half of the vanilla bean.
![]() ![]() ![]() Share: Press the Share icon to cast a photo or video to the TV screen for others to view in a larger size. #Hisense qview for windows android‘Grabbed’ notification: Each time a user ‘grabs’ content (which can only be accessed when the content owner ‘enables’ the Grab feature) an on-screen notification briefly displays the person’s name or Gmail address associated with his or her Android device.Use it to enable others to access the piece of content that you’ve shared to the TV. Grab: The Grab feature is disabled by default.Toggle Play: Use the Toggle feature to navigate the screen and play or pause content.‘Joined’ notification: Each time someone joins in to share their content, his or her name (or Gmail address associated with the Android device) briefly appears on the TV screen.Built-in (and easy) tutorial: The simplistic design of this app enables first-time users to begin enjoying it without the need for instructions however, this short tutorial is available in the unlikely event that you need assistance.Owners of these TVs simply need a mobile phone or tablet running Android 4.1 or above and an Internet connection. Hisense Qview comes pre-installed on Hisense H7B Series 4K UHD Smart TVs. Download Hisense Qview now to get started! Simply upload your favorite videos or photos into the queue (which holds 50 pieces of content at a time) and then view them one after the other on your Hisense Series 4K UHD Smart TV. This app is unique because it enables multiple users to share multiple pieces of their content to the TV at the same time! If you’re planning a small gathering or large party, then Hisense Qview is the perfect way for everyone in attendance to share the spotlight together. The next time you feel like taking a stroll down memory lane through your favorite photos and videos, invite others to join in alongside you through this FREE sharing app. Hisense Qview comes pre-installed on Hisense 4K UHD Smart TVs. ![]() ![]() This episode of Face Off, Original vs Remake edition is written by Eric Walkuski, narrated by Shawn Knippelberg, and edited by Lance Vlcek. But which of these films will survive and what will be left of them? Only one way to find out: FACE OFF! The remake is still a nasty piece of work, even it’s if more polished than the original. Upon its release, it made a killing at the box office and launched a franchise that includes the 2003 Michael Bay-produced remake The Texas Chainsaw Massacre starring Jessica Biel. How much of The Texas Chainsaw Massacre is based on the real life murderer Ed Gein Despite being heavily touted as 'inspired by a true story,' both Tobe Hooper's original 1974 film and the 2003 Marcus Nispel remake are only lightly based on the real-life murderer Ed Gein, who is suspected to have taken several victims between 19. The Texas Chain Saw Massacre is a 1974 American slasher film, directed and produced by Tobe Hooper, who cowrote it with Kim Henkel. I’m talking about the one that started it all, Tobe Hooper’s The Texas Chainsaw Massacre (1974), which featured a handful of unknown actors and was produced on a shoe-string budget. Plot: Five teens take a trip through Texas to check on their grandfathers grave during a rash of ritualistic grave desecrations. Released in October 1974, Tobe Hooper’s The Texas Chainsaw Massacre was one of the first slasher movies to gain popular recognition, and it started a slasher-movie craze that would define horror films in the 80s. Marilyn Burns plays Sally in Tobe Hooper’s The Texas Chainsaw Massacre (1974). But now that the big boy has released yet another sequel into the world, it’s time to look back at the two main entries in the franchise - and apologies to those who hold the bonkers 1986 sequel near and dear to their hearts. 16 Trivia Facts About ‘The Texas Chainsaw Massacre’ (1974) Stephen King wrote, I would happily testify to its redeeming social merit in any court in the country. ![]() On the way they stumble across what appears to be a. Partain, Edwin Neal, Jim Siedow, Allen Danziger. Nothing supernatural here - unless you count the startling amount of times he’s been rebooted, or how tangled the timeline of his mayhem has become. Five friends head out to rural Texas to visit the grave of a grandfather. The Texas Chainsaw Massacre is a film directed by Tobe Hooper with Marilyn Burns, Paul A. ![]() It is all the more tragic in that they were young. ![]() What makes him stand apart from the likes of Freddy, Jason, Chucky, and other slashers is the fact that he’s just a human being. Opening Narrative of the 1974 film, The Texas Chainsaw Massacre: LISTEN to the Monologue (video) 'The film which you are about to see is an account of the tragedy that befell a group of five youths, in particular Sally Hardesty and her invalid brother, Franklin. THE TEXAS CHAIN SAW MASSACRE 1974 STORY MOVIEWhen it comes to horror movie icons, Leatherface might be head (or face) and shoulders above the rest. ![]() ![]()
![]() ![]() I mean, what more can you ask for from a foundation! Wet N Wild 10 Pan Palette Review Wet n Wild 5 Pan Palette – Heart & Sol It’s a charming foundation, and it’s at a drugstore price. Sometimes with foundation they look like they’re just sitting on top of the skin. One thing that I notice when I use this foundation is that it looks so skin-like. #Best drugstore concealer skinMy skin is more normal, but I thought the dry part might make it a little bit more hydrating for over 50 mature skin. It’s an absolute holy grail for so many people. This foundation is one of the best drugstore foundations. Revlon Colorstay Foundation Revlon Colorstay Foundation ![]() It’s a beautiful, sophisticated color that is just perfect for the winter months. I’ve recently tried the City Beauty Plumping Lip Gloss in Plum Springs, and I’m so over the moon for this color. Use Code PRETTYOVER50 for 15% off sitewide ![]() So it has a chance to sink into my lips and soften the lines and give me a little more volume. I put this lipgloss on before I start doing my makeup. However, it plumps them up a little bit and removes the lines on my lips. This is a plumping lipgloss, but it doesn’t plump my lips up like if I were a 30 year old. I wasn’t sure about this product at first, but now that I’ve tried it, I appreciate it so much in my beauty routine. One of the big hits for me this year has been my City Beauty Clear Plumping Lipgloss. City Beauty Products Reviews Use Code PRETTYOVER50 for 15% off sitewide If you do use my links, I appreciate your support. It doesn’t cost you anything extra and you are free to use the link or not as you choose. If you click a link and buy something, I receive a commission for the sale. ![]() ![]() New gene editing technologies have the potential to circumvent some of the problems associated with viral gene-addition. No family background of cancer in childhood. HSC GT for PID has been in development for the last two decades and the first licensed HSC-GT product for adenosine deaminase-deficient severe combined immunodeficiency (ADA-SCID) is now available.Or failure of a HLA HAPLO-identical bone marrow transplant within 10 years after transplantation.Presence of a severe infection: pneumonitis and / or chronic diarrhea, or infection with herpes viruses or parainfluenza type 3 or adenovirus, or disseminated BCG infection, or presence of severe diarrhea and a severe compromise of the general state with denutrition.This period could be shortened if the probability to find a donor is low or if the clinical situation (gravity) required No HLA identical family donor and no HLA identical unrelated donor (10/10 antigens) found in the 6 weeks following the beginning of the search.Diagnosis of classical SCID-X1 based on immunophenotype (absent, or reduced numbers of non-functional T lymphocytes) and confirmed by DNA sequencing.Boys diagnosed during the first year of life.biological efficacy assessment of this new vector SIN, assessment of molecular characteristics of retroviral integration.longitudinal evaluation of clinical effects in terms of improvement or complete restoration of immunity.assessment of immune reconstitution : phenotype, number and function of different T, NK and B cells subpopulations.efficacy assessment of ex vivo transduction of CD34 + hematopoietic stem cells of the patient through the use of retroviral vector.safety assessment : clinical effects, possible emergence of clonal lymphocyte proliferation, potential activation of proto-oncogene.Secondary goals are the evaluation of immune reconstitution allowing the cure of infections present at the time of gene therapy, assessment of integration sites, and finally the long-term correction of immunosuppression. The main purpose of the study is the study of toxicity: tolerance and incidence of serious adverse effects. 2 of SCID-X1 must be as efficient than the previous one but must involve a risk of insertional mutagenesis significantly reduced as compared to the first protocol. The objective of this protocol is to reinitiate an ex vivo gene therapy clinical protocol to treat patients with SCID-X1 without HLA identical family donor nor HLA identical unrelated donor (bone marrow and cord blood) available in an adequate time with the clinical conditions of the patient at diagnosis (approximately 6 weeks). Why Should I Register and Submit Results?.© 2020 British Society for Haematology and John Wiley & Sons Ltd. Gene therapy primary immunodeficiencies stem cell transplantation. In this review, we discuss the development of HSC GT for PID and outline the current state of clinical development before discussing future developments in the field. HSC GT for PID shows great promise, but requires a unique approach for each disease and carries risks, notably insertional mutagenesis from gamma-retroviral gene addition approaches and possible off-target toxicities from gene-editing techniques. HSC GT for PID has been in development for the last two decades and the first licensed HSC-GT product for adenosine deaminase-deficient severe combined immunodeficiency (ADA-SCID) is now available. Autologous haematopoietic stem cell gene therapy (HSC GT) has the potential to correct genetic defects across haematopoietic lineages without the complications of an allogeneic approach. Allogeneic haematopoietic stem cell transplantation (alloHSCT) is curative for many PIDs, and while advances have resulted in improved outcomes, the procedure still carries a risk of mortality and morbidity from graft failure or graft-versus-host disease (GvHD). ![]() Many PIDs are devastating and require a definitive therapy to prevent progressive morbidity and premature mortality. Primary immunodeficiencies (PIDs) are a group of rare inherited disorders of the immune system. ![]() ![]() ![]() Unfortunately, it looks like there is no premium subscription to get rid of ads at the moment. What we didn’t like about the app is that it has a lot of ads. The first drawback is that it is supported by ads and it comes with only two voice choices. There are some drawbacks to using this free app though. The software analyzes your voice to perform the optimal voice change effects so you sound as close to normal as you can. You can use this free voice changer program to change your voice from man to woman and vice versa. You can use the built-in voices and sound effects to sound like a man, woman, child, robot, or any of the other supported voices. MorphVox is a free audio effect tool that can change your voice. Works with several apps like TeamSpeak, Mumble, Steam, Skype, Google Chat If you are looking for a free voice changer program for Discord, this might be the one. The effects list includes Alien, Atari, Robot, male, female, baby, and radio among others. The app is also pretty easy to set up and use. #Female voice changer app mods#While ClownFish cannot match the number of voice mods provided by applications like VoiceMod, the effects that it does bring are fairly nice. So, apart from Discord, you can use ClownFish in apps like TeamSpeak, Mumble, Steam, Skype, Google Chat, and more. The app can be installed at the system level so any application that uses your microphone can be made to use your modified voice. #Female voice changer app full#Pricing: Free trial, $99.95 for a full licenseĬlownFish is a free voice changer for Windows that you can use to change your voice while chatting on Discord. ![]() Option to record your morphed voice and edit it in the waveform It is available in three different versions – Basics, Gold, and Diamond, which you can choose from depending on your budget and requirement. #Female voice changer app driver#The software also comes with advanced virtual driver technology which makes it compatible with most VoIP programs, role-playing games, and web chat applications. ![]() Your voice can sound deeper, higher, younger, older, more feminine, more masculine, more robotic, or modified in any way you like. ![]() ![]() ğeel realistic turbulence of wind while airplane is in the air. ![]() Ěmazing graphics with realistic effects of fog, day, night, etc. For this, keeping an eye on the timings of the planes taking off and landing is important. You are required to manage the take of the planes according to their flight timings, assign a taxi way, assign the runway for takeoff, line up airplanes for takeoff, and provide green signal for takeoff.Īvoid Collision: While managing the air traffic as well as ground traffic of the aircrafts, you have to make sure the planes do not collide. Take Off: Several airplanes also await your instructions to take off from the airport. You are supposed to queue the airplanes according to their arrival time, check if the landing strip is engaged, assign a taxi way, assign gate number to park the plane, and give clearance for landing. Landing: As a number of planes wait to land at the airport, your job is to assign landing to these planes. Let us take a look at the game-play options and the features of this amazing app: UNMATCHED AIR TRAFFIC CONTROL SEM BAIXAR SIMULATORAll these features make this simulator app very entertaining as well as engaging at the same time. Unmatched Air Traffic Control comes loaded with a host of features and game-play options. Realistic simulations, excellent graphics, multiplayer option, and easy controls make this app a really desirable one. With more than 5 million installs and 4+ rating, Unmatched Air Traffic Control is one of the best simulation games available out there. Moreover, you will need to manage runway operations, taxi way, and gates according to the various airplane models from Boeing and Airbus. Being a busy airport, it gets air traffic from different airlines and various parts of the world. Being a simulator, it gives its players the actual feel of operating air traffic on a busy airport. Have you ever wondered how one can download Unmatched Air Traffic Control PC? Dont worry, we’re going to break it down on your behalf into simple and easy steps.Ī realistic Air Traffic Control simulation game, Unmatched Air Traffic Control lets you control the airplanes flying in and flying out from an airport. UNMATCHED AIR TRAFFIC CONTROL SEM BAIXAR INSTALLdesigned Unmatched Air Traffic Control app to work with Google Android along with iOS however, you should be able to install Unmatched Air Traffic Control on PC or MAC. BrowserCam presents Unmatched Air Traffic Control for PC (computer) download for free. ![]() ![]() ![]() It doesn’t do much, but at least you can say that you have it. Mearn and its forms are the equivalent of having a rare adorable plush animal. But at level 34, players will see it transform into Feliblandqo, a taller, stronger, and less creepy version than what you’re used to. At level 17, you see it turn into Masqat, which has a respectable group of stats. Masquiti’s evolve forms make the unfriendly starter a worthy pick. We know Masquiti is almost too creepy, but as a psychic monster, you shouldn’t be too shocked. If you’re having trouble against water-types, then maybe consider Marasuma or Raksuma in these tough spots. Furthermore, its rarity may be solely based on their look, as their abilities aren’t any better than those of others on this list. Great plant-types are ultra-rare to come by in Extinction, which is ironic as that’s what Mara and its evolve forms are classified as. It’s not the toughest final form out there, but its 37 HP after evolving is really enticing. However, Noocidal deserves the biggest spotlight, as the final form looks familiar to that of a legendary Pokemon. Heddeca looks even more frightening than its former self, and it is much tougher. Behilda evolutionsĭesign-wise, we’re convinced that Behilda has the most promise. Reptomotor is also excellently designed and built with 37 HP, 30 attack, and 28 defense when evolved. Kamelevo is a well-balanced second-form, with 22 HP, 21 attack, and 18 defense. Dealing with its first form is also a burden, but Kamelevo and its final evolve form Reptomotor make it clear that hard work pays off. We think running with Gekoko is very much like running with Noki. I guess Noki isn’t a bad choice after all – if you’re the patient type. ![]() You can obtain Hainok at level 36, with its initial stats being 33 HP, 30 attack, 28 defense, and 10 speed. Though its evolve forms, Vainok and Hainok, turn the baby Nexomon from cute to badass – and its stats show it too. Yes, Noki is notorious for being one of the weaker starters, but it’s probably one of the cutest. Once it hits level 34, it’ll become the gorgeous Lumerei, with a 32 attack stat and a 27 defense stat. For any Nexomon leveled in the teens, that’s actually pretty outstanding – but it doesn’t stop there. At level 17, Lume becomes Lumefur, which has an average attack stat of 23. We’ve said before that Lume is likely the best among all starters in the game, and its future forms are no different. ![]() So, here is a look at all starter evolutions and their respective strengths. It’s a nice touch, but your decision should be made by how each starter develops with each evolve form. Every option represents a different element, so psychic and normal die-hards can rejoice. Unlike other monster-collectors though, Nexomon: Extinction gives you a likely record-high nine starters to pick from. Sometimes we may or may not choose starter monsters based on how cool their evolve forms seem – we’re all guilty of it. ![]() |
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